Biopharmaceutics and Clinical Pharmacokinetics 4th edn (PB)

This book deals with the basics, of the two disciplines of biopharmaceutics and pharmacokinetics. Different factors such as biological, physiochemical and formulation that influence the therapeutic efficacy of a drug are covered in biopharmaceutics. The absorption, distribution, metabolism and excretion of drugs are studied under this subject. Basics of biopharmaceutics and pharmacokinetics help to understand the various procedures and advances in drug design, product development, therapeutic drug monitoring, etc. The pharmacokinetics part of this book covers the fundamentals of one compartment open model, multi-compartmental models. One compartment open model is presented in an elaborate manner to make the students familiar with various aspects of pharmacokinetics. Mathematical equations are developed using simple integration and differentiation methods to enable the students to understand the concepts easily. Practice problems are provided where ever necessary, and a question bank is included at the end of each chapter to enhance student s knowledge. Extreme care has been exercised to present the concepts in a simple way. Every biological scientist should have knowledge in statistics in order to assess the significance of the results of his experiments. Hence, a chapter on biostatistics with practice problems is included in the book.