FUNDAMENTALS OF DATA MINING IN GENOMICS AND PROTEOMICS

As natural phenomena are being probed and mapped in ever-greater detail, scientists in genomics and proteomics are facing an exponentially growing vol­ ume of increasingly complex-structured data, information, and knowledge. Ex­ amples include data from microarray gene expression experiments, bead-based and microfluidic technologies, and advanced high-throughput mass spectrom­ etry. A fundamental challenge for life scientists is to explore, analyze, and interpret this information effectively and efficiently. To address this challenge, traditional statistical methods are being complemented by methods from data mining, machine learning and artificial intelligence, visualization techniques, and emerging technologies such as Web services and grid computing. There exists a broad consensus that sophisticated methods and tools from statistics and data mining are required to address the growing data analysis and interpretation needs in the life sciences.